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1. A physician suspects that a patient's symptoms are related to abrupt discontinuation of a certain drug and asks the pharmacotherapy specialist about common reactions in this type of situation.
A literature search produces one case report of a discontinuation syndrome involving the drug.
What is the most appropriate action to take with regard to the current suspected adverse event?
A) Complete a manufacturer's adverse event report.
B) Report the event to the FDA MedWatch program.
C) Report the event to the P & T Committee.
D) Write and submit a case report detailing the event.
2. A patient is admitted to the hospital after a motor vehicle collision. The patient takes methadone
40 mg once daily for management of an opiate addiction. The remainder of the patient's medical history is unremarkable. The medical resident caring for the patient wants to order methadone but Expresses concern related to the Substance Abuse and Mental Health Services Administration (SAMHSA) regulations.
What is the appropriate action?
A) Order morphine at equivalent dose as an alternative management.
B) Order methadone 40 mg once daily if the patient shows signs of withdrawal.
C) Order methadone 40 mg once daily if the medical resident is a registered opioid treatment program (OTP) practitioner.
D) Order methadone 40 mg once daily during inpatient treatment.
3. Which of the following is a risk factor for the development of multidrug resistance in pathogens that cause nosocomial pneumonia?
A) Current hospitalization for the past 3 days
B) Antimicrobial therapy implemented 6 months ago
C) Hemodialysis initiated 2 days ago
D) Home infusion therapy that includes antibiotics
4. The pharmacotherapy specialist-directed research team in a large healthcare system plans to submit a comparative effectiveness study proposal in response to the request for proposals released under the Patient Protection and Affordable Care Act. In designing this study, which category of outcomes should be used for the primary endpoint?
A) Cost-effectiveness
B) Surrogate markers
C) Patient-centered health
D) Cost savings
5. A study is conducted comparing two antibiotics for the treatment of UTIs. The results after 7 days of therapy demonstrated that Drug A was superior to Drug B in eradicating bacteria from the urine and eliminating signs and symptoms of infections. The investigators concluded that Drug A was significantly superior to Drug B (p<0.05). In subsequent studies, however, the two drugs were equivalent in efficacy.
Which one of the following types of error apparently occurred in the first study?
A) Regression to the mean
B) Beta error
C) Type |
D) Type ||
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: D | Question # 3 Answer: C | Question # 4 Answer: C | Question # 5 Answer: C |
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